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Updated: Jan 18, 2026

Coherent anti-Stokes Raman Scattering CARS Microscopy Visualizes Pharmaceutical Tablets During Dissolution
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Solid-State Quantification of Cocrystals in Pharmaceutical Tablets Using Transmission Low-Frequency Raman

Motoki Inoue1, Takumi Osada1, Hiroshi Hisada1

  • 1Department of Molecular Pharmaceutics , Meiji Pharmaceutical University , 2-522-1, Noshio , Kiyose, Tokyo 204-8588 , Japan.

Analytical Chemistry
|October 1, 2019
PubMed
Summary

Low-frequency Raman spectroscopy accurately quantifies pharmaceutical cocrystal content in tablets. This method effectively distinguishes cocrystals from raw materials, ensuring product quality during continuous manufacturing.

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