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Updated: Jan 18, 2026

A Closed-Type Wireless Nanopore Electrode for Analyzing Single Nanoparticles

A Closed-Type Wireless Nanopore Electrode for Analyzing Single Nanoparticles

Published on: March 20, 2019

How Nanoparticles Transform Single Molecule Measurements into Quantitative Sensors.

Yanfang Wu^1,2,3, Danielle Bennett^1,2,3, Richard D Tilley^1,2

¹School of Chemistry, The University of New South Wales, Sydney, NSW, 2052, Australia.

Advanced Materials (Deerfield Beach, Fla.)

|October 1, 2019

Summary

Nanoparticles enable simultaneous near-field measurements, advancing single-molecule analysis for quantitative sensing. This breakthrough paves the way for next-generation sensing technologies utilizing nanoparticle-based strategies.

Keywords:

digital counting quantitative analysis single molecule detection single molecule sensors single nanoparticle assays

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Last Updated: Jan 18, 2026

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Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems

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Published on: July 4, 2011

Area of Science:

Biophysics
Analytical Chemistry
Nanotechnology

Background:

Single molecule measurements are crucial for understanding molecular behavior stochastics.
Current near-field approaches utilize small measurement volumes for high local concentrations.
Performing numerous single molecule measurements concurrently is the next frontier for quantitative analysis.

Purpose of the Study:

To discuss coupled developments in nanoparticles and measurement strategies.
To highlight how nanoparticles can form the basis of next-generation sensing technologies.

Main Methods:

Utilizing nanoparticles to create numerous near-field volumes.
Simultaneous measurement of these near-field volumes.

Main Results:

Nanoparticles facilitate the creation of multiple, measurable near-field volumes.
This approach enables parallel single molecule measurements.

Conclusions:

Nanoparticle-enhanced near-field measurements are key to advancing quantitative single molecule analysis.
This integrated approach positions nanoparticles as foundational elements for future sensing technologies.