The predictive value of PRECISE-DAPT score for arrhythmic complications in patients with ST-elevation myocardial
Ersin Yildirim1, Ceyhan Turkkan2, Kazim Serhan Ozcan2
1Department of Cardiology, University of Health Sciences, Istanbul Umraniye Education and Research Hospital.
Insights
The PRECISE-DAPT score predicts arrhythmias like high-degree atrioventricular block and atrial fibrillation in ST-segment elevation myocardial infarction patients after percutaneous coronary intervention.
Area of Science:
- Cardiology
- Clinical Prediction Models
Background:
- ST-segment elevation myocardial infarction (STEMI) is a critical condition requiring prompt intervention.
- Percutaneous coronary intervention (PCI) is the standard treatment for STEMI.
- Arrhythmias are common complications following PCI in STEMI patients.
Purpose of the Study:
- To evaluate the PRECISE-DAPT score's ability to predict arrhythmias in STEMI patients undergoing primary PCI.
- To determine if a higher PRECISE-DAPT score is associated with an increased risk of in-hospital arrhythmias.
Main Methods:
- A cohort of 706 STEMI patients undergoing primary PCI was analyzed.
- Patients were stratified into two groups based on the PRECISE-DAPT score (≥25 vs. <25).
- In-hospital arrhythmia development was compared between the two groups.
Main Results:
- Patients with a PRECISE-DAPT score ≥25 had significantly higher rates of high-degree atrioventricular block (17.2% vs. 4.9%), ventricular tachycardia (11.2% vs. 4.6%), and atrial fibrillation (13.8% vs. 3.1%).
- Ventricular fibrillation rates did not differ significantly between groups (9.5% vs. 8.3%).
- Multivariable analysis confirmed PRECISE-DAPT score as an independent predictor of high-degree atrioventricular block (OR: 6.38) and atrial fibrillation (OR: 4.33).
Conclusions:
- The PRECISE-DAPT score is a valuable tool for predicting the risk of high-degree atrioventricular block and atrial fibrillation in STEMI patients post-PCI.
- Higher PRECISE-DAPT scores are associated with increased arrhythmia risk, aiding in risk stratification and patient management.
Objective:
To investigate the predictive value of the PRECISE-DAPT score for the development of arrhythmias in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.
Method:
A total of 706 patients with a diagnosis of ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention were enrolled to the study. The patients were divided into two groups according to the PRECISE-DAPT score (PRECISE-DAPT score ≥25 and PRECISE-DAPT score <25). The patients were compared in terms of in-hospital arrhythmia.
Results:
High-degree atrioventricular block (second-degree Mobitz II or third-degree atrioventricular block) (17.2% vs. 4.9%; P < 0.001), ventricular tachycardia (11.2% vs. 4.6%; P = 0.005) and atrial fibrillation (13.8% vs. 3.1%; P < 0.001) rates were statistically higher in patients with higher PRECISE-DAPT score (≥25). There was no difference between the groups in terms of ventricular fibrillation (9.5% vs. 8.3%; P = 0.678). In multivariable logistic regression analysis; PRECISE-DAPT Score was independently associated with high-degree atrioventricular block (odds ratio: 6.38, P < 0.001) and atrial fibrillation (odds ratio: 4.33, P < 0.001).
Conclusion:
The PRECISE-DAPT score was associated with high-degree atrioventricular block and atrial fibrillation in patients with ST-segment elevation myocardial infarction underwent percutaneous coronary intervention.
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