Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Flourine-18 Prostate-Specific Membrane Antigen-1007 Positron Emission Tomography Imaging in Staging of Primary and Secondary Prostate Cancer-A Retrospective Observational Cohort Study.

JU open plus·2026

Same author

The PRAGMATIC pathway - PRostate cancer diAGnosis and MAnagement Triage In Clinical care.

BJU international·2026

Same author

Circulating tumour cells as a window into lethality in prostate cancer.

Nature reviews. Urology·2026

Same author

Cost Effectiveness of Local Anaesthetic Transperineal Versus Transrectal Biopsy: Results from the TRANSLATE Study.

European urology focus·2025

Same author

Single-cell analysis uncovers preserved prostate cancer lineages and universally altered pathways in Matrigel-free patient-derived organoids.

Cell reports·2025

Same author

Local anaesthetic transperineal biopsy versus transrectal prostate biopsy in prostate cancer detection (TRANSLATE): a multicentre, randomised, controlled trial.

The Lancet. Oncology·2025

Same journal

Role and relevance of genetic testing in patients with kidney stones: a review from EAU Section of Endourology.

Current opinion in urology·2026

Same journal

Advances in evaluating and delivering nontechnical skills training: The use of simulation, robotics, artificial intelligence and virtual reality.

Current opinion in urology·2026

Same journal

Educating for a sustainable future: faculty and student perspectives and a review of environmental sustainability in medical education - an EAU endourology study.

Current opinion in urology·2026

Same journal

Shaping the future of endourology: role of education, simulation and uro-technology: a scoping review by the EAU Section of Endourology.

Current opinion in urology·2026

Same journal

A review of emerging technologies and techniques for percutaneous nephrolithotomy access.

Current opinion in urology·2026

Same journal

Artificial intelligence in kidney cancer: a review of clinical applications across the disease spectrum.

Current opinion in urology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 18, 2026

Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking

Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking

Published on: November 17, 2023

Optimizing prostate biopsy techniques.

Altan Omer^1,2, Alastair D Lamb^1,3

¹Department of Urology, Oxford University Hospitals NHS Foundation Trust, Oxford.

Current Opinion in Urology

|October 1, 2019

Summary

This summary is machine-generated.

Advances in prostate cancer diagnostics, including multiparametric MRI and transperineal biopsies, aim to improve detection of clinically significant prostate cancer while reducing unnecessary procedures. New techniques offer safer, more accurate biopsies.

More Related Videos

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

Published on: October 10, 2019

Related Experiment Videos

Last Updated: Jan 18, 2026

Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking

Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking

Published on: November 17, 2023

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

Published on: October 10, 2019

Area of Science:

Urology
Oncology
Radiology

Background:

Prostate cancer (PCa) diagnostics evolve to better detect clinically significant PCa (csPCa) and reduce indolent cancer detection.
Multiparametric MRI (mpMRI) and active surveillance have reshaped PCa diagnosis, reducing biopsy needs but increasing accuracy demands.

Purpose of the Study:

Review studies impacting PCa diagnostic knowledge and clinical practice.
Analyze shifts in PCa diagnostic strategies and their clinical implications.

Main Methods:

Review of studies on evolving PCa diagnostic techniques.
Analysis of the impact of mpMRI and new biopsy approaches on clinical practice.

Main Results:

mpMRI improves PCa prediction, leading to lesion-targeted biopsies (PI-RADS 3-5).
Transperineal (TP) biopsies under local anesthesia (LATP) address limitations of transrectal ultrasound (TRUS) biopsies, such as infection and missed anterior lesions.
LATP shows potential to become the standard for front-line diagnostic biopsies within five years.

Conclusions:

Evolving diagnostic tools like mpMRI and targeted biopsies enhance csPCa detection.
Transperineal biopsies under local anesthesia represent a significant advancement, improving safety and accuracy.
Future PCa diagnostics will likely prioritize minimally invasive, accurate, and targeted biopsy techniques.