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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
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Contrast Sensitivity and Glaucoma.

Parul Ichhpujani1, Sahil Thakur2, George L Spaeth3

  • 1Glaucoma Service, Department of Ophthalmology, Government Medical College & Hospital, Chandigarh, Punjab, India.

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|October 1, 2019
PubMed
Summary

Spatial contrast sensitivity declines in glaucoma, impacting vision. This review covers assessment methods, its role in glaucoma development, and clinical use.

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Area of Science:

  • Ophthalmology
  • Neuroscience

Background:

  • Glaucoma is a progressive optic neuropathy characterized by visual field loss.
  • Spatial contrast sensitivity (SCS) is a key visual function often impaired in glaucoma patients.

Purpose of the Study:

  • To review methods for assessing spatial contrast sensitivity.
  • To explore the role of SCS in glaucoma pathogenesis.
  • To discuss the clinical applications of SCS testing in glaucoma management.

Main Methods:

  • Literature review of studies on contrast sensitivity testing in glaucoma.
  • Analysis of the relationship between SCS deficits and glaucoma progression.
  • Evaluation of the utility of SCS in clinical glaucoma diagnosis and monitoring.

Main Results:

  • Various psychophysical methods exist for measuring SCS, with differing sensitivities.
  • SCS decline is a common finding across different glaucoma types and stages.
  • SCS impairment correlates with disease severity and may precede structural damage.

Conclusions:

  • Spatial contrast sensitivity is a valuable functional measure in glaucoma.
  • SCS assessment aids in early detection, disease staging, and treatment monitoring.
  • Integrating SCS testing into routine clinical practice can improve patient outcomes.