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Acne, retinoids, and dermabrasion.
The Journal of Dermatologic Surgery and Oncology
|April 1, 1985
Summary
Oral 13-cis-retinoic acid effectively treated severe nodulocystic acne vulgaris in nine patients. Subsequent full-face dermabrasion showed normal healing and no significant complications, indicating a safe and effective combined treatment approach.
Area of Science:
- Dermatology
- Dermatologic Surgery
Background:
- Severe nodulocystic acne vulgaris presents a significant therapeutic challenge.
- Retinoid therapy is a cornerstone treatment for severe acne.
- Acne scarring often necessitates further intervention after active disease control.
Purpose of the Study:
- To evaluate the efficacy and safety of oral 13-cis-retinoic acid in treating severe nodulocystic acne vulgaris.
- To assess the outcomes of full-face dermabrasion performed during or after retinoid therapy for acne scarring.
Main Methods:
- Nine patients with severe nodulocystic acne vulgaris received oral 13-cis-retinoic acid.
- All patients underwent full-face dermabrasion either during or after the retinoid treatment course.
Main Results:
- Complete clearance of acne vulgaris was observed in all nine patients following treatment with oral 13-cis-retinoic acid.
- Postoperative healing after dermabrasion was uneventful.
- No significant complications were reported during the healing process post-dermabrasion.
Conclusions:
- Oral 13-cis-retinoic acid is highly effective for treating severe nodulocystic acne vulgaris.
- Full-face dermabrasion is a safe and well-tolerated procedure in patients treated with or completing retinoid therapy for acne.
- The combination of retinoid therapy and subsequent dermabrasion offers a viable treatment strategy for severe acne and associated scarring.