Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

AgNPs-Cellulose Nanofiber/Polyacrylamide Hydrogels as an Antibacterial Platform for Soft Tissue.

Gels (Basel, Switzerland)·2026
Same author

Editorial: Host-microbiota interactions in IBD: immune modulation and barrier function.

Frontiers in cellular and infection microbiology·2026
Same author

Editorial: Maternal nutrition, gut microbiota, and endocrine programming in early life.

Frontiers in endocrinology·2026
Same author

Across the Social Network of the Gut: Bacterial, Fungal, and Viral Determinants of Checkpoint Inhibitor Efficacy and Toxicity.

International journal of molecular sciences·2026
Same author

Exploratory Statistical Analyses of Clinical and Biochemical Factors for Differentiated Thyroid Cancer from a Romanian Cohort.

Cancers·2026
Same author

Correction: Cernencu et al. 3D Bioprinting of Biosynthetic Nanocellulose-Filled GelMA Inks Highly Reliable for Soft Tissue-Oriented Constructs. <i>Materials</i> 2021, <i>14</i>, 4891.

Materials (Basel, Switzerland)·2026

Related Experiment Video

Updated: Jan 6, 2026

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

19.6K

Functional Polyimide-Based Electrospun Fibers for Biomedical Application.

Diana Serbezeanu1, Tăchiță Vlad-Bubulac2, Daniela Rusu2

  • 1"Petru Poni" Institute of Macromolecular Chemistry, Aleea Grigore Ghica Voda, 41A, 700487 Iasi, Romania. diana.serbezeanu@icmpp.ro.

Materials (Basel, Switzerland)
|October 2, 2019
PubMed
Summary
This summary is machine-generated.

Electrospun polyimide fibers show excellent biocompatibility, promoting enhanced L929 fibroblast cell viability and proliferation for potential biomedical applications like wound healing patches.

Keywords:
Live-Dead testMTT testanti-biofilm activityantimicrobial propertiesdermal fibroblastselectrospun polyimide fibers

More Related Videos

Vapor Phase Deposition of Electroactive Poly(3,4-ethylenedioxythiophene) onto Electrospun Commodity Polymer Nanofibers
08:28

Vapor Phase Deposition of Electroactive Poly(3,4-ethylenedioxythiophene) onto Electrospun Commodity Polymer Nanofibers

Published on: March 7, 2025

1.7K
Synthesis of Keratin-based Nanofiber for Biomedical Engineering
14:43

Synthesis of Keratin-based Nanofiber for Biomedical Engineering

Published on: February 7, 2016

15.9K

Related Experiment Videos

Last Updated: Jan 6, 2026

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

19.6K
Vapor Phase Deposition of Electroactive Poly(3,4-ethylenedioxythiophene) onto Electrospun Commodity Polymer Nanofibers
08:28

Vapor Phase Deposition of Electroactive Poly(3,4-ethylenedioxythiophene) onto Electrospun Commodity Polymer Nanofibers

Published on: March 7, 2025

1.7K
Synthesis of Keratin-based Nanofiber for Biomedical Engineering
14:43

Synthesis of Keratin-based Nanofiber for Biomedical Engineering

Published on: February 7, 2016

15.9K

Area of Science:

  • Biomaterials Science
  • Materials Science
  • Biomedical Engineering

Background:

  • Biocompatible materials are crucial for advanced biomedical applications.
  • Electrospun polyimide fibers offer a promising matrix for tissue engineering and regenerative medicine.

Purpose of the Study:

  • To evaluate the cytotoxicity of electrospun polyimide fiber membranes.
  • To assess the viability and proliferation of L929 murine fibroblasts on these fibers.

Main Methods:

  • Cytotoxicity assays were performed on L929 murine fibroblasts in direct contact with electrospun polyimide fibers.
  • Cell viability and proliferation were quantified over two and six days.
  • Confocal microscopy visualized cell proliferation tendencies.
  • Scanning electron microscopy (SEM) assessed membrane morphological stability in phosphate-buffered saline (PBS).

Main Results:

  • Significantly increased cell viability and proliferation were observed on electrospun polyimide fibers compared to the control.
  • Confocal microscopy confirmed a tendency for cells to proliferate on the material.
  • SEM analysis indicated good morphological stability of the polyimide membrane after PBS immersion.

Conclusions:

  • Electrospun polyimide fiber membranes demonstrate excellent biocompatibility and support cell growth.
  • These findings support the potential of electrospun polyimide fibers as scaffolds for biomedical applications, including wound healing.
  • The ease of production further enhances their future development potential.