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[Testosterone level in male patients with coronary heart disease and essential hypertension]

A Y Kravchenko1, V M Provotorov1

  • 1Voronezh State Medical University.

Problemy Endokrinologii
|October 2, 2019
PubMed

Insights

Low testosterone (androgen deficiency) is common in men under 60 with heart disease or hypertension. This deficiency correlates with waist size and inversely with cholesterol and depression.

Area of Science:

  • Endocrinology
  • Cardiology
  • Metabolic Syndrome

Context:

  • Age-related androgen deficiency is increasingly recognized.
  • Coronary heart disease (CHD) and essential hypertension are significant public health concerns.
  • Understanding risk factors associated with these conditions is crucial for effective management.

Purpose:

  • To determine the prevalence of age-related androgen deficiency in men under 60 with CHD or essential hypertension.
  • To investigate the association between testosterone levels and cardiovascular risk factors including cholesterol, adiposity, and depression.

Summary:

  • The study assessed 107 male patients (mean age 50.2 years) with CHD or essential hypertension.
  • Mean testosterone levels were indicative of androgen deficiency (9.2±0.96 n/mol/l).
  • Testosterone showed a direct correlation with waist circumference and inverse correlations with atherogenic lipoproteins and depression.

Impact:

  • Findings suggest a link between low testosterone and cardiovascular disease risk factors in younger men.
  • Highlights the potential role of androgen deficiency as a contributing factor or marker in CHD and hypertension.
  • May inform future research and clinical strategies for managing cardiovascular health in aging men.

Keywords:
adiposityandrogen deficiencycoronary heart diseaseessential hypertensionmale sex

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