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Published on: July 19, 2024
Comparison of the Utilities of Cryobiopsy and Forceps Biopsy for Peripheral Lung Cancer
Shingo Nasu1, Norio Okamoto2, Hidekazu Suzuki2
1Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan hugurahoma@yahoo.co.jp.
Background/Aim:
This study aimed to compare the efficacies of cryobiopsy and forceps biopsy for peripheral lung cancer detection.
Patients And Methods:
A retrospective review of peripheral lung cancer cases between December 2017 and April 2019 was conducted. Forceps biopsy was performed followed by cryobiopsy using a guide sheath (GS). Diagnostic yields were compared between cryobiopsy and forceps biopsy.
Results:
A total of 53 lung cancer lesions were evaluated. The diagnostic yields of forceps biopsy and cryobiopsy were 86.8% and 81.1%, respectively. Univariate and multivariate analyses indicated that cryobiopsy with a GS was significantly associated with increased diagnostic yield (odds ratio(OR)=11.6; p=0.044). Among the four patients who tested positive on cryobiopsy and negative on forceps biopsy, one had diffused pulmonary metastases and the others showed intratumoural air bronchograms.
Conclusion:
Cryobiopsy using a GS can significantly increase diagnostic yield and help identify lesions with intratumoural air bronchograms and external wall lesions.
