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[Aortic valve degenerative disease with patent ductus arteriosus infective endocarditis: A case report]

Guiyang Chen1, Liying Gong2, Hanying Liu3

  • 1Department of Cardiology, Third Xiangya Hospital, Central South University, Changsha 410013, China.

Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences
|October 2, 2019
PubMed

Insights

This case study highlights infective endocarditis (IE) where aortic valve vegetations detached, traveled through a patent ductus arteriosus (PDA), causing lung lesions. Prompt antibiotic treatment resolved the pulmonary infection.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Infective endocarditis (IE) involves microbial infection of heart valves, frequently causing vegetations.
  • Pulmonary manifestations of IE are uncommon, often presenting as septic emboli.

Observation:

  • A 49-year-old female presented with prolonged fever and a lung cavity on CT, initially suspected as inflammation or tuberculosis.
  • Echocardiography revealed aortic valve vegetations and an abscess, with surgery uncovering a patent ductus arteriosus (PDA).

Findings:

  • The patient was diagnosed with valvular degeneration with infection, with coccus identified in pathological tissue.
  • Post-surgical treatment with vancomycin, sensitive to Enterococcus faecalis, led to significant absorption of the lung lesion.

Implications:

  • This case illustrates a rare presentation of IE where aortic valve vegetations embolized to the lungs via a PDA.
  • It underscores the importance of considering IE in patients with unexplained fever and pulmonary lesions, especially with concurrent cardiac abnormalities.
Abstract

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