Diarrhoea, Hyperpigmentation and Hamartomatous Polyposis Syndrome
Shubham Jain1, Ravi Thanage1, Pravin M Rathi2
1Senior Resident.
Abstract:
Cronkhite-Canada syndrome (CCS)is a rare non-hereditary hamartomatous polyposis syndrome of unknown aetiology. It is characterized by diffuse gastrointestinal polyps, dystrophic nail changes, alopecia, cutaneous hyperpigmentation, chronic diarrhoea, anorexia and hypogeusia. It is associated with a high incidence of gastrointestinal malignancies, mortality and morbidity. Early clinical suspicion and treatment is important. We report an elderly male with CCS who showed clinical and endoscopic improvement with long term corticosteroid therapy.
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