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Related Concept Videos

Vaccinations01:51

Vaccinations

51.1K
Overview
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Development of Immunocompetence01:22

Development of Immunocompetence

759
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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Teratogenicity01:07

Teratogenicity

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Cancer Vaccines01:30

Cancer Vaccines

917
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
917
Active versus Passive Immunity01:31

Active versus Passive Immunity

9.8K
Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
9.8K
Transcytosis of IgG01:15

Transcytosis of IgG

4.0K
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
4.0K

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Related Experiment Video

Updated: Jan 6, 2026

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus
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Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus

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[Vaccination During Pregnancy].

Michèle Stahel1

  • 1Klinik für Geburtshilfe, Frauenklinik Zürich.

Praxis
|October 2, 2019
PubMed
Summary

Vaccinations during pregnancy protect mothers and newborns from serious infectious diseases. Routine immunizations like influenza and pertussis (whooping cough) are recommended for maternal and infant health.

Area of Science:

  • Obstetrics and Gynecology
  • Pediatrics
  • Immunology

Background:

  • Pregnant women face increased risks for severe illness from certain infectious diseases.
  • Newborns are particularly vulnerable to severe complications and mortality from specific infections in early infancy.

Purpose of the Study:

  • To highlight the importance and benefits of maternal vaccinations.
  • To identify key vaccines recommended during pregnancy for optimal protection.

Main Methods:

  • Review of current vaccination guidelines for pregnant individuals.
  • Analysis of disease risks and vaccine efficacy in maternal and infant populations.

Main Results:

  • Influenza vaccination primarily protects the pregnant mother from severe illness.
Keywords:
GrippeimpfungImpfungPertussisimpfungSchwangerschaftVaccinationgrossesseinfluenza vaccinationpertussis vaccinationpregnancyvaccination contre la coqueluchevaccination contre la grippe

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  • Pertussis (whooping cough) vaccination effectively shields infants from severe complications and mortality during the critical first three months of life.
  • Conclusions:

    • Maternal immunization is a crucial strategy for preventing infectious diseases in both mothers and newborns.
    • Routine vaccination against influenza and pertussis during pregnancy offers significant public health benefits.