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Updated: Jan 6, 2026

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum
Published on: August 5, 2020
[Death within Hours]
Rahel Maria Kindler1, Marc Kuster1, Doris Madörin1
1Departement Perioperative Medizin Kantonsspital Olten.
Abstract:
Death within Hours Abstract. The clinical picture of invasive meningococcal disease is broad, it mostly manifests as meningitis and/or sepsis. The severity ranges from a simple bacteremia associated with mild, unspecific symptoms to fulminant sepsis with multiorgan failure and death, which happens in 10-15 % of cases. Sometimes purely local infections (e.g. septic arthritis or conjunctivitis) or rarely a chronic course (prolonged, intermittent fever, rash, arthritis and headache) are the only clinical manifestation - which can also lead to a disseminated fulminant disease. Our case illustrates the tragic progression of a fulminant meningococcal sepsis with rapid death.
Insights
Invasive meningococcal disease can rapidly progress to fatal sepsis. This case highlights the severe and swift progression of meningococcal sepsis, leading to death within hours.
Area of Science:
- Medicine
- Microbiology
- Infectious Diseases
Background:
- Invasive meningococcal disease (IMD) presents with diverse clinical manifestations, primarily meningitis and sepsis.
- IMD severity ranges from mild bacteremia to fulminant sepsis with multiorgan failure and death (10-15% of cases).
- Local infections or chronic courses can precede fulminant disseminated disease.
Purpose of the Study:
- To illustrate the rapid and fatal progression of invasive meningococcal disease.
- To emphasize the potential for swift deterioration in meningococcal sepsis.
Main Methods:
- Case report presentation.
- Clinical observation and documentation of disease progression.
Main Results:
- The case demonstrated a fulminant course of meningococcal sepsis.
- Rapid progression to death occurred within hours.
Conclusions:
- Invasive meningococcal disease, particularly sepsis, can lead to rapid mortality.
- Prompt recognition and management are critical in severe meningococcal infections.
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