Related Experiment Video
Updated: Jan 6, 2026

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
Macular edema associated with non-infectious uveitis: pathophysiology, etiology, prevalence, impact and management
Horace Massa1, Spyros Y Pipis2, Temilade Adewoyin2
1Department of Ophthalmology, Geneva University Hospitals, Geneva, Switzerland.
Abstract:
Macular edema (ME) is the most common sight-threatening complication in uveitis. The diagnostic and therapeutic management of the uveitic macular edema (UME) might be challenging due to the complex diagnostic workup and the difficulties physicians face to find the underlying cause, and due to its usually recurrent nature and the fact that it can be refractory to conventional treatment. Some of the mild cases can be treated with topical steroids, which can be combined with non-steroid anti-inflammatory drugs. However, immunomodulators such as methotrexate, tacrolimus, azathioprine, cyclosporine and mycophenolate mofetil together with anti-tumor necrosis factor-α (anti-TNF alpha) monoclonal antibodies such as adalimumab and infliximab, may be required to control the inflammation and the associated ME in refractory cases, or when an underlying disease is present. This review of the literature will focus mostly on the non-infectious UME.
Related Concept Videos
Glaucoma: Overview
Nephrotic Syndrome II : Assessment and Medical Management
Nephrotic Syndrome I : Introduction
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Nephrotic Syndrome III : Nursing Management
Angle Closure Glaucoma: Treatment

