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Electrocardiographic left ventricular hypertrophy and mortality in an oldest-old hypertensive Chinese population

Rui Chen1, Kunhao Bai2, Fanghong Lu3

  • 1Renal Division, Department of Medicine, Peking University First Hospital, Beijing, People's Republic of China.

Clinical Interventions in Aging
|October 2, 2019
PubMed

Insights

Electrocardiographic left ventricular hypertrophy (ECG LVH) predicts cardiovascular mortality in hypertensive individuals aged 80 and older. This finding is crucial for understanding mortality risks in the oldest-old population.

Area of Science:

  • Cardiology
  • Gerontology
  • Hypertension Research

Background:

  • Electrocardiographic left ventricular hypertrophy (ECG LVH) is linked to mortality.
  • Limited data exists on ECG LVH's correlation with mortality in the oldest-old hypertensive population.

Purpose of the Study:

  • To investigate the association between ECG LVH and mortality in hypertensive Chinese individuals aged 80 years and older.

Main Methods:

  • Included 284 hypertensive Chinese participants (age >80 years).
  • Defined ECG LVH using Sokolow-Lyon voltage criteria (>3.5 mV).
  • Utilized Cox regression models to assess mortality risks.

Main Results:

  • A 28-month follow-up revealed 35 deaths (12.3%), with 21 cardiovascular deaths.
  • ECG LVH was associated with increased cardiovascular mortality (adjusted HR 4.25).
  • ECG LVH did not significantly predict all-cause mortality (adjusted HR 2.31).

Conclusions:

  • ECG LVH is a significant predictor of cardiovascular mortality in the oldest-old hypertensive Chinese population.
Abstract

Keywords:
Chinahypertensionleft ventricular hypertrophymortalityoldest-old

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