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Updated: Jan 6, 2026

Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent
Published on: May 8, 2017
Optical Molecular Imaging of Inflammatory Cells in Interventional Medicine-An Emerging Strategy
Gavin P Birch1,2, Thane Campbell2, Mark Bradley1
1EaStChem School of Chemistry, University of Edinburgh, Edinburgh, United Kingdom.
Abstract:
The optical molecular imaging of inflammation is an emerging strategy for interventional medicine and diagnostics. The host's inflammatory response and adaptation to acute and chronic diseases provides unique signatures that have the potential to guide interventions. Thus, there are emerging a suite of molecular imaging and sensing approaches for a variety of targets in this area. This review will focus on two key cellular orchestrators that dominate this area, neutrophils and macrophages, with recent developments in molecular probes and approaches discussed.
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