Real time continuous glucose monitoring in neonatal intensive care

Kathryn Beardsall1

  • 1University Department of Paediatrics, University of Cambridge, Box 116 Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK; The Neonatal Unit, Rosie Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Early Human Development
|October 3, 2019
PubMed

Insights

Continuous glucose monitoring (CGM) reveals frequent, silent glucose issues in newborns, impacting outcomes. This technology shows promise for improving neonatal intensive care unit (NICU) glucose management.

Area of Science:

  • Neonatal Medicine
  • Endocrinology
  • Medical Technology

Background:

  • Hypoglycaemia and hyperglycaemia are prevalent in critically ill infants, linked to adverse outcomes.
  • Current glucose monitoring is infrequent, leading to management controversies.
  • Continuous glucose monitoring (CGM) is standard in adults/children for dysglycaemia management.

Purpose of the Study:

  • To explore the role and potential of CGM in neonatal intensive care units (NICUs).
  • To assess glucose regulation insights provided by CGM in newborns.
  • To evaluate CGM's safety and efficacy in targeting glucose control in preterm infants.

Main Methods:

  • Application of CGM technology in neonatal populations.
  • Analysis of glucose variability and dysglycaemia patterns in newborns.
  • Review of ongoing clinical trials investigating CGM in preterm infants.

Main Results:

  • CGM demonstrates significant, often undetected, hypoglycaemia and hyperglycaemia in neonates.
  • Baseline CGM data is crucial for assessing glucose dysregulation's long-term impact.
  • Preliminary studies indicate CGM can be used safely to guide glucose control in preterm infants.

Conclusions:

  • CGM offers valuable insights into neonatal glucose regulation, identifying silent dysglycaemia.
  • Despite current technological limitations for NICU use, CGM holds significant future potential for neonatal care.
  • Ongoing research and technological advancements are expected to enhance CGM's role in managing infant glucose levels.

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