Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.6K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: A novel extracellular role for tissue transglutaminase in matrix-bound VGF-mediated angiogenesis.

Cell death & disease·2026
Same author

Correction: Argon plasma surface modification promotes the therapeutic angiogenesis and tissue formation of tissue-engineered scaffolds in vivo by adipose-derived stem cells.

Stem cell research & therapy·2025
Same author

Post-Pneumonectomy Syndrome.

Irish medical journal·2025
Same author

Management strategies following recurrence of resected retroperitoneal sarcoma: A 10-year observational study.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2025
Same author

A Randomised Phase II Trial of Hippocampal Sparing Versus Conventional Whole Brain Radiotherapy After Surgical Resection or Radiosurgery in Favourable Prognosis Patients With 1-10 Brain Metastases.

Clinical oncology (Royal College of Radiologists (Great Britain))·2024
Same author

Comparative assessment of radiation therapy-induced vasculitis using [<sup>18</sup>F]FDG-PET/CT in patients with non-small cell lung cancer treated with proton versus photon radiotherapy.

European journal of nuclear medicine and molecular imaging·2023

Related Experiment Video

Updated: Jan 6, 2026

Experimental Approaches to Tissue Engineering
16:41

Experimental Approaches to Tissue Engineering

Published on: August 30, 2007

6.7K

Breast Reconstruction with a Tissue Engineering and Regenerative Medicine Approach (Systematic Review).

E Donnely1, M Griffin2,3, P E Butler2,3

  • 1Division of Surgery and Interventional Science, University College London, Royal Free Hospital Campus, London, UK. Edward.donnely10@alumni.imperial.ac.uk.

Annals of Biomedical Engineering
|October 3, 2019
PubMed
Summary

Tissue engineering offers a novel approach to breast reconstruction, utilizing scaffolds and cells to regenerate tissue. Further research is needed to optimize vascularity and tissue composition for larger volumes.

Keywords:
Adipose-derived stem cellsBreast reconstructionCellular therapyRegenerative medicineScaffoldStem cellsTissue engineering

More Related Videos

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

4.0K
Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats
08:56

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats

Published on: February 10, 2020

7.5K

Related Experiment Videos

Last Updated: Jan 6, 2026

Experimental Approaches to Tissue Engineering
16:41

Experimental Approaches to Tissue Engineering

Published on: August 30, 2007

6.7K
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

4.0K
Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats
08:56

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats

Published on: February 10, 2020

7.5K

Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Plastic and Reconstructive Surgery

Background:

  • Current breast reconstruction methods (autologous flaps, implants) have limitations and can cause morbidity.
  • Tissue engineering presents a promising alternative for breast reconstruction, aiming to minimize donor-site morbidity.

Purpose of the Study:

  • To systematically review the literature on tissue engineering approaches for breast reconstruction.
  • To explore the use of scaffolds, cells, and growth factors in regenerating breast tissue.

Main Methods:

  • Systematic literature search of Medline and Embase databases.
  • Inclusion of 28 articles, primarily in vitro and animal studies (level-5 evidence).
  • Analysis of biological (collagen, decellularized matrix) and synthetic (polymers) scaffolds.

Main Results:

  • Scaffolds support new tissue growth; synthetic scaffolds offer customizable designs.
  • Adipose-derived stem cells and basic fibroblast growth factor investigated for enhanced regeneration.
  • A human case series reported successful regeneration of 210 mL tissue using a tissue engineering chamber.

Conclusions:

  • Tissue engineering demonstrates potential for breast reconstruction with various scaffold types.
  • Further research is crucial to enhance regenerated tissue composition and vascularity for larger volume reconstruction.