Related Experiment Video
Updated: Jan 6, 2026

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods
Published on: December 23, 2013
The More the Merrier: When Four Interfaces Are Better Than One
1Department of Biochemistry, McGill University, Montreal, QC H3G 0B1, Canada.
Abstract:
In this issue of Structure, Zhou et al. (2019) determine the crystal and solution structures of iASPP bound to PP1. The proteins interact through a discontinuous interface defined by four contact points. Association/dissociation of individual contacts enables the transition between multiple conformations and provides mechanistic insight into how ASPPs regulate phosphorylation of p53.
Related Concept Videos
Controller Configurations
Control-system compensation involves various configurations, most commonly series or cascade compensation, in which the controller...
Design Example
Protein-protein Interfaces
Multiple Pipe Systems
Series Configuration
In a series configuration, fluid flows sequentially from one pipe...
Integrator and Differentiator
An integrator within an op-amp circuit produces an output directly proportional to the integral of the input signal. This is achieved by replacing the feedback resistor in a typical inverting...
Interfacial Electrochemical Methods: Overview

