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Updated: Jan 6, 2026

Genetic Engineering of an Unconventional Yeast for Renewable Biofuel and Biochemical Production
Published on: September 20, 2016
mSphere of Influence: the Power of Yeast Genetics Still Going Strong!
1Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA fsantiago@nd.edu.
Abstract:
Felipe Santiago-Tirado studies the cell biology of cryptococcal infections. In this mSphere of Influence article, he reflects on how the papers "Systematic Genetic Analysis of Virulence in the Human Fungal Pathogen Cryptococcus neoformans" (https://doi.org/10.1016/j.cell.2008.07.046) and "Unraveling the Biology of a Fungal Meningitis Pathogen Using Chemical Genetics" (https://doi.org/10.1016/j.cell.2014.10.044) by the Noble and Madhani groups influenced his thinking by showcasing the various modern applications of yeast genetics in an organism where genetic manipulation was difficult.
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