Ventricular volume expansion in presymptomatic genetic frontotemporal dementia

Tamara P Tavares¹, Derek G V Mitchell¹, Kristy Coleman¹+21

• ¹From the Graduate Program in Neuroscience and Brain and Mind Institute (T.P.T., D.G.V.M., E.C.F.) and Departments of Clinical Neurological Sciences (C.S., E.C.F.) and Medical Biophysics (R.B.), Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario; Parkwood Institute (K.C., E.C.F.), Lawson Health Research Institute, London, Canada; Dementia Research Centre, Department of Neurodegenerative Disease (D.M.C., K.M.M., J.D.R.), UCL Institute of Neurology, Queen Square; Centre for Medical Image Computing (D.M.C.), University College London, UK; Department of Neurology (J.v.S.), Erasmus Medical Center, Rotterdam, the Netherlands; Neurology Unit, Department of Clinical and Experimental Sciences (B.B.), University of Brescia; Department of Pathophysiology and Transplantation (D.G.), "Dino Ferrari" Center, University of Milan, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Italy; Toronto Western Hospital (M.C.T.), Tanz Centre for Research in Neurodegenerative Disease, Canada; Department of Clinical Neurosciences (J.R.), University of Cambridge, UK; Department NVS (C.G.), Center for Alzheimer Research, Division of Neurogenetics, Karolinska Institutet, Sweden; Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Istituto Neurologico Carlo Besta (F.T.), Milan; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Centro San Giovanni di Dio Fatebenefratelli (G.F., S.C.), Brescia, Italy; Memory Clinic and LANVIE-Laboratory of Neuroimaging of Aging (G.F.), University Hospitals and University of Geneva, Switzerland; Clinique Interdisciplinaire de Mémoire, Département des Sciences Neurologiques (R.L.), CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Faculty of Medicine (A.d.M.), University of Lisbon, Portugal; Department of Neuroscience, Psychology, Drug Research and Child Health (S.S.), University of Florence, and the IRCCS Foundazione Don Carlo Gnocchi (S.S.), Florence, Italy; Statistics & Data Corporation (G.W.), Tempe, AZ; and LC Campbell Cognitive Neurology Research Unit (M.M.), Department of Medicine, Division of Neurology, Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, Toronto, Canada.+1