MRI-guided percutaneous needle biopsy with 1.2T open MRI: study protocol for a prospective feasibility study...

Area of Science:

• Medical Imaging
• Interventional Radiology
• Biomedical Engineering

Background:

• Open MRI systems offer patient accessibility but often have limited imaging quality due to lower field strength.
• High-field (1.2T) open MRI systems are emerging, aiming to combine superior image quality with improved patient access.
• MRI-guided percutaneous needle biopsy is a developing interventional technique requiring precise device navigation.

Purpose of the Study:

• To evaluate the feasibility of performing MRI-guided percutaneous needle biopsy using a novel 1.2T high-field open MRI system.
• To assess the safety and efficacy of this new MRI system for interventional procedures.
• To determine the potential for wider adoption of MRI-guidance in biopsy procedures.

Main Methods:

• A feasibility trial involving ten patients requiring percutaneous needle biopsy for pathological diagnosis.
• Real-time MR-fluoroscopy guidance was used for biopsy needle insertion.
• The primary endpoint was successful needle placement within the target lesion, confirmed by needle notch visualization.

Main Results:

• The study aims to validate the feasibility of accurate biopsy needle insertion under real-time MR-fluoroscopy.
• Secondary endpoints include monitoring for adverse events, device failures, and successful specimen acquisition.
• Successful validation could pave the way for broader use of this technology.

Conclusions:

• The 1.2T high-field open MRI system demonstrates potential for safe and accurate MRI-guided percutaneous needle biopsy.
• Successful validation may encourage the widespread adoption of MRI-guidance for biopsy and other interventional procedures.
• This technology could drive further development in MRI-guided interventions.