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Extraction of Histones from Clinical Specimens for Epigenetic Profiling by Mass Spectrometry
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Epigenetic drug target deconvolution by mass spectrometry-based technologies.

Roberta Noberini1, Tiziana Bonaldi2

  • 1Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milano, Italy.

Nature Structural & Molecular Biology
|October 5, 2019
PubMed
Summary

Target deconvolution identifies all molecule targets, crucial for drug discovery. Mass spectrometry technologies now enable this process, particularly in epigenetic drug discovery.

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