Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

4.9K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
4.9K
Bone Remodeling01:40

Bone Remodeling

40.2K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
40.2K
Bone Disorders01:29

Bone Disorders

5.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.0K
The Bone Matrix01:18

The Bone Matrix

5.4K
Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in...
5.4K
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

9.9K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
9.9K
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

3.8K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Naloxone Training Among Sorority-Affiliated College Students: An Observational Study.

The American journal of nursing·2026
Same author

A Practical Guide to Implementing an Evidenced-Based Hands-On Naloxone Training.

Journal of community health nursing·2024
Same author

Antihypertensive Teach-Back to Reduce Delays, Cancellations, and Interventions in a Freestanding Gastroenterology Clinic.

Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates·2023
Same author

An exploratory study of a hands-on naloxone training for rural clinicians and staff.

Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing·2022
Same author

Down Syndrome: A Review of Key Perioperative Implications.

AORN journal·2022
Same author

Reducing Hypothermia After Cardiac Ablation Using the ASPAN Normothermia Guidelines.

Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses·2022

Related Experiment Video

Updated: Jan 6, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

13.2K

Understanding Bone Cement Implantation Syndrome.

Cheryl B Hines1

  • 1is a staff anesthetist at Northport Medical Center in Northport, Alabama.

AANA Journal
|October 5, 2019
PubMed
Summary

Bone cement implantation syndrome (BCIS) is a rare but serious complication of cemented bone surgery. Understanding its causes and presentation is key to preventing severe outcomes like cardiac arrest.

Area of Science:

  • Orthopedic Surgery
  • Anesthesiology
  • Cardiology

Background:

  • Bone cement implantation syndrome (BCIS) is a rare, potentially fatal perioperative complication.
  • It can range from mild hypotension to cardiac arrest, significantly increasing mortality in femoral neck fracture patients.

Purpose of the Study:

  • To provide a comprehensive review of bone cement and BCIS.
  • To consolidate understanding of BCIS etiology, pathophysiology, and clinical presentation.
  • To outline strategies for risk reduction in cemented procedures.

Main Methods:

  • Literature review of bone cement history and associated hazards.
  • Analysis of BCIS etiology, pathophysiology, and clinical manifestations.
  • Examination of preoperative assessment, anesthetic management, and surgical risk reduction.
Keywords:
Anesthesiaarthroplastybone cement implantation syndromemethyl methacrylate

More Related Videos

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
11:51

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage

Published on: February 10, 2014

15.9K
Author Spotlight: Innovative Methodology for Implanting and Securing Neural Probes in the Rodent Spinal Cord
04:35

Author Spotlight: Innovative Methodology for Implanting and Securing Neural Probes in the Rodent Spinal Cord

Published on: July 12, 2024

2.0K

Related Experiment Videos

Last Updated: Jan 6, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

13.2K
An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
11:51

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage

Published on: February 10, 2014

15.9K
Author Spotlight: Innovative Methodology for Implanting and Securing Neural Probes in the Rodent Spinal Cord
04:35

Author Spotlight: Innovative Methodology for Implanting and Securing Neural Probes in the Rodent Spinal Cord

Published on: July 12, 2024

2.0K

Main Results:

  • BCIS pathophysiology involves right ventricular failure due to increased pulmonary artery pressure.
  • Clinical presentations vary widely, from transient desaturation to fatal cardiac events.
  • Risk factors and management strategies are discussed based on existing literature.

Conclusions:

  • A thorough understanding of BCIS is crucial for perioperative management.
  • Preoperative planning, anesthetic techniques, and surgical practices can mitigate BCIS risks.
  • Further research into BCIS etiology and pathophysiology is warranted.