Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

7.4K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
7.4K
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention01:05

Bioavailability Enhancement: Drug Stability Enhancement and GI Retention

174
Body:Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
174
Bioavailability Enhancement: Drug Solubility Enhancement01:16

Bioavailability Enhancement: Drug Solubility Enhancement

194
Body:Bioavailability is a critical factor in determining a drug's effectiveness. It refers to the proportion of a drug that enters the circulation when introduced into the body and is, as a result, able to have an active effect. Enhancing bioavailability is essential for drugs with poor solubility, as it can significantly impact their therapeutic efficacy. Various methods are employed to increase the solubility of drugs, thereby enhancing their bioavailability.Micronization and nanonization are...
194
Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules01:18

Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules

262
Bioequivalence in generic drugs, such as tablets and capsules, refers to their pharmaceutical equivalence to the brand-name counterparts. However, for therapeutic equivalence, manufacturers must also consider physical attributes like size, shape, and weight (FDA Guidance for Industry, December 2003). Discrepancies in these aspects could impact patient compliance and cause medication errors. For instance, swallowing difficulties, often experienced with larger tablets or capsules, can lead to...
262
Mineral, Vitamin and Water Absorption01:27

Mineral, Vitamin and Water Absorption

1.3K
Electrolytes are essential minerals and ions primarily obtained from the diet and absorbed through the gastrointestinal tract. Most electrolytes are absorbed in the small intestine. While the absorption of iron and calcium primarily occurs in the duodenum, calcium is also absorbed in the jejunum and ileum. In these regions, passive diffusion contributes to its absorption alongside active transport mechanisms in the duodenum. These ions can exit the enterocytes through specialized active...
1.3K
Biopharmaceutical Factors Influencing Drug Product Design: Overview01:22

Biopharmaceutical Factors Influencing Drug Product Design: Overview

212
Rational drug product design integrates knowledge of the drug’s physicochemical properties, formulation components, manufacturing techniques, and intended route of administration. Each factor influences the drug’s performance, including how it is released, absorbed, and eliminated in the body.The physicochemical properties of a drug—such as solubility, stability, and particle size—affect its compatibility with excipients and the choice of dosage form. Excipients, though...
212

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reverse rendezvous endoscopic retrograde cholangiopancreatography after liver partition and portal vein ligation.

Endoscopy·2026
Same author

Brassinolide-mediated physiological and biochemical adaptation in rye (Secale cereale L.) under aluminum and freeze-thaw stress.

Journal of the science of food and agriculture·2026
Same author

Citric acid enhances physiological and biochemical tolerance of rye (<i>Secale cereale</i> L.) seedlings to cadmium toxicity and repeated freeze-thaw cycles.

Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering·2026
Same author

Early-Onset Hyponatremia Presenting as Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) Post-transsphenoidal Pituitary Resection.

Cureus·2026
Same author

Global renal infarction from main renal artery occlusion in under-anticoagulated atrial fibrillation: A case report.

Radiology case reports·2026
Same author

Interactive effects of cadmium stress and freeze-thaw cycles on Secale cereale L.: Protective role of exogenous betaine.

Ecotoxicology and environmental safety·2026

Related Experiment Video

Updated: Jan 6, 2026

Author Spotlight: Process Development for the Spray-Drying of Probiotic Bacteria and Evaluation of the Product Quality
05:45

Author Spotlight: Process Development for the Spray-Drying of Probiotic Bacteria and Evaluation of the Product Quality

Published on: April 7, 2023

4.2K

Vitamin D microencapsulation and fortification: Trends and technologies.

Vaibhav Kumar Maurya1, Khalid Bashir2, Manjeet Aggarwal1

  • 1Department of Basic and Applied Sciences, National Institute of Food Technology, Entrepreneurship and Management, Kundli, Sonepat, 131028, Haryana, India.

The Journal of Steroid Biochemistry and Molecular Biology
|October 6, 2019
PubMed
Summary

Global vitamin D deficiency is widespread. Nanotechnology offers solutions for effective vitamin D (Vit D) food fortification, overcoming challenges in bioavailability and stability.

Keywords:
BioavailabilityEncapsulationFortificationFunctional foodMicro-/nano-encapsulationVitamin D

More Related Videos

Extraction of Plant-based Capsules for Microencapsulation Applications
10:54

Extraction of Plant-based Capsules for Microencapsulation Applications

Published on: November 9, 2016

12.4K
Production of Near-Infrared Sensitive, Core-Shell Vaccine Delivery Platform
06:27

Production of Near-Infrared Sensitive, Core-Shell Vaccine Delivery Platform

Published on: October 20, 2020

5.6K

Related Experiment Videos

Last Updated: Jan 6, 2026

Author Spotlight: Process Development for the Spray-Drying of Probiotic Bacteria and Evaluation of the Product Quality
05:45

Author Spotlight: Process Development for the Spray-Drying of Probiotic Bacteria and Evaluation of the Product Quality

Published on: April 7, 2023

4.2K
Extraction of Plant-based Capsules for Microencapsulation Applications
10:54

Extraction of Plant-based Capsules for Microencapsulation Applications

Published on: November 9, 2016

12.4K
Production of Near-Infrared Sensitive, Core-Shell Vaccine Delivery Platform
06:27

Production of Near-Infrared Sensitive, Core-Shell Vaccine Delivery Platform

Published on: October 20, 2020

5.6K

Area of Science:

  • Food Science and Technology
  • Nutritional Science
  • Nanotechnology

Background:

  • Vitamin D (Vit D) deficiency is a global health concern, prevalent even in sunny regions due to various factors.
  • Limited dietary sources and significant losses during food processing hinder adequate Vit D intake.
  • Vit D is crucial for preventing chronic diseases beyond bone health.

Purpose of the Study:

  • To review current vitamin D (Vit D) status and recommended dietary allowances (RDA).
  • To explore challenges in food fortification with Vit D.
  • To examine the role of nanotechnology and microencapsulation in enhancing Vit D bioavailability and stability in fortified foods.

Main Methods:

  • Literature review on vitamin D deficiency, RDA, and fortification challenges.
  • Analysis of microencapsulation techniques (liposomes, solid-lipid particles, nanostructured lipid carriers, etc.) for Vit D.
  • Evaluation of nanomaterial-based Vit D fortification in food matrices.

Main Results:

  • Nanotechnology-based microencapsulation techniques show promise for overcoming Vit D fortification hurdles.
  • These techniques can improve homogeneity, reduce degradation, and enhance stability of Vit D in food products.
  • Development of Vit D-nanomaterials offers a viable strategy for effective food fortification.

Conclusions:

  • Nanotechnology provides innovative solutions for the challenges associated with vitamin D (Vit D) food fortification.
  • Microencapsulation techniques are key to developing stable and bioavailable Vit D-fortified foods.
  • Further research into Vit D-nanomaterials is essential for addressing global Vit D deficiency through food fortification.