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Updated: Jan 6, 2026

Live Imaging of Nicotine Induced Calcium Signaling and Neurotransmitter Release Along Ventral Hippocampal Axons
Published on: June 24, 2015
Film-based fluorescence sensing: a "chemical nose" for nicotine
Ke Liu1, Jing Zhang1, Ling Xu1
1Key Laboratory of Applied Surface and Colloid Chemistry (Ministry of Education), School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710119, P. R. China. liuth121@snnu.edu.cn yfang@snnu.edu.cn.
Abstract:
A novel series of emissive o-carborane derivatives, which showed multicolor, highly solid-state emission (ΦF ≥ 43%) and ideal photochemical stability, were synthesized. Inspired by the powerful mammalian olfactory system, we, for the first time, successfully obtained a fluorescent sensor array, which exhibits superior detection capability for nicotine in the gaseous phase (down to 3 ppb). Furthermore, the sensor array can be extended to detect nicotine in aqueous solution at the nano-gram level (∼0.1 ng cm-2) and determine the smoke of cigarette and electronic cigarette.
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