[Quantitative whole-body skeletal scintigraphy with a gamma camera and pinhole collimator]

Quantitative evaluation of whole-body bone scans is valuable for the description of metabolic activity in systemic bone disease and provides parameters of whole-body activity retention up to 24 h after injection of the radiopharmacon, of bone to soft tissue relation and of the activity in the epiphysis and diaphysis. A combination of whole-body imaging by a gamma-camera with pinhole collimator and a series of single pictures evaluated by the ROI technique is able to record these parameters with sufficient precision. This is demonstrated by measuring phantoms, and patients with and without bone disease. In 34 patients with systemic bone disease the quantitative parameters are altered partially, the changes however are insufficient for their differential diagnosis.