Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Immediate hypersensitivity to quinine].

I Pin, P J Dor, D Vervloet

    Presse Medicale (Paris, France : 1983)
    |April 27, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Weaning from noninvasive ventilatory support in infants with severe bronchiolitis: An observational study.

    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2023
    Same author

    Clinical implications of isolated troponinemia following immune checkpoint inhibitor therapy.

    ESMO open·2021
    Same author

    Has the introduction of high-flow nasal cannula modified the clinical characteristics and outcomes of infants with bronchiolitis admitted to pediatric intensive care units? A retrospective study.

    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2020
    Same author

    Enzyme-replacement therapy in perinatal hypophosphatasia: Case report and review of the literature.

    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2018
    Same author

    [Post-traumatic pulmonary aspergilloma].

    Revue des maladies respiratoires·2018
    Same author

    The asthma-rhinitis multimorbidity is associated with IgE polysensitization in adolescents and adults.

    Allergy·2018
    Same journal

    Predictive analytics and risk stratification models in internal medicine: from risk scores to real-time machine learning.

    Presse medicale (Paris, France : 1983)·2026
    Same journal

    Artificial Intelligence in skin disease therapeutics: from drug discovery to personalized treatment pathways.

    Presse medicale (Paris, France : 1983)·2026
    Same journal

    AI in clinical diagnostics in dermatology: applications, validation, and real-world use cases.

    Presse medicale (Paris, France : 1983)·2026
    Same journal

    Artificial Intelligence in medical research and publishing: progress, risks, and future perspectives.

    Presse medicale (Paris, France : 1983)·2026
    Same journal

    Ethical, legal, and regulatory challenges in AI-based healthcare tools.

    Presse medicale (Paris, France : 1983)·2026
    Same journal

    Decision-making for clinicians.

    Presse medicale (Paris, France : 1983)·2026
    See all related articles

    Quinine in antipyretic medication can cause severe allergic reactions, including anaphylaxis and shock. Skin tests and radioallergosorbent tests confirmed quinine as the trigger via an immediate hypersensitivity mechanism.

    Area of Science:

    • Pharmacology
    • Immunology
    • Allergy Research

    Background:

    • Antipyretic combination products are widely used for fever and pain relief.
    • Understanding drug-induced hypersensitivity is crucial for patient safety.
    • Quinine is an active ingredient found in some antipyretic formulations.

    Observation:

    • A patient experienced a severe systemic anaphylactic reaction, including shock, after consuming an antipyretic product.
    • The reaction was temporally associated with the ingestion of the quinine-containing medication.

    Findings:

    • Immediate skin tests confirmed hypersensitivity to quinine.
    • Oral challenge tests further validated quinine as the causative agent.
    • Radioallergosorbent testing (RAST) detected specific IgE antibodies, confirming an immediate hypersensitivity mechanism.

    Related Experiment Videos

    Implications:

    • This case highlights the potential for quinine to induce severe allergic reactions.
    • Clinicians should consider quinine allergy in patients presenting with anaphylaxis after antipyretic use.
    • Further research into quinine hypersensitivity mechanisms and diagnostic tools is warranted.