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Updated: Jan 6, 2026

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
Published on: May 7, 2019
Nontraumatic Spinal Cord Compression: MRI Primer for Emergency Department Radiologists.
Olga Laur1, Hari Nandu1, David S Titelbaum1
1From the Departments of Radiology (O.L., D.B.N.), Neuroradiology (H.N., D.B.N.), and Emergency Radiology (B.K.), Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115; and Department of Radiology, Shields Health Care, Brockton, Mass (D.S.T.).
Acute myelopathy requires prompt diagnosis via spinal MRI to differentiate causes. Identifying spinal cord compression and edema is crucial for urgent treatment and preventing permanent disability.
Area of Science:
- Radiology
- Neurology
- Emergency Medicine
Background:
- Acute myelopathy in a non-traumatic setting is a medical emergency.
- Spinal MRI is the primary diagnostic tool for evaluating acute myelopathy.
- Accurate diagnosis is critical to prevent permanent neurological deficits.
Purpose of the Study:
- To outline the differential diagnoses of acute myelopathy.
- To differentiate between compressive and non-compressive causes of myelopathy.
- To emphasize the importance of MRI findings in guiding urgent patient management.
Main Methods:
- Review of spinal MRI findings in acute myelopathy.
- Categorization of myelopathy by spinal canal compartment: epidural, intradural extramedullary, and intramedullary.
- Correlation of imaging findings with clinical and laboratory data.
Main Results:
- Compressive myelopathy shows thecal sac effacement and epidural fat obliteration.
- Non-compressive myelopathy presents as intramedullary T2-hyperintensity without a mass.
- A compartmental MRI approach aids in localizing lesions and refining diagnoses.
Conclusions:
- Spinal MRI is essential for diagnosing acute nontraumatic myelopathy.
- Differentiating compressive from non-compressive causes guides treatment decisions.
- Timely diagnosis and management are key to improving patient outcomes.
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