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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Related Experiment Video

Updated: Jan 6, 2026

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NCCN Guidelines Insights: Multiple Myeloma, Version 1.2020.

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|October 8, 2019
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Summary
This summary is machine-generated.

The NCCN Guidelines for Multiple Myeloma offer updated recommendations for diagnosing and treating multiple myeloma and related conditions. This summary focuses on key changes in the 1.2020 version for improved patient care.

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Area of Science:

  • Hematology
  • Oncology
  • Nephrology

Background:

  • Multiple myeloma and related plasma cell disorders require updated clinical guidance.
  • Monoclonal gammopathy of renal significance presents unique diagnostic and management challenges.

Framework:

  • The NCCN Guidelines for Multiple Myeloma provide a comprehensive framework.
  • Recommendations cover diagnosis, workup, treatment, follow-up, and supportive care.

Implementation:

  • This summary highlights key updates from the 1.2020 version of the NCCN Guidelines.
  • Focus on changes relevant to monoclonal gammopathy of renal significance, solitary plasmacytoma, smoldering myeloma, and multiple myeloma.

Implications:

  • These updated guidelines aim to standardize and improve care for patients with multiple myeloma.
  • Adoption of these recommendations can lead to better patient outcomes and management strategies.