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Primary Ewing's Sarcoma of Maxillary sinus: A Case Report
Chauhan Richa1, Trivedi Vinita1, Kumari Nishi1
1Mahavir Cancer Sansthan, Patna, Bihar, India.
The Gulf Journal of Oncology
|October 9, 2019
Summary
Ewing's sarcoma, a rare bone cancer in children, can occur in the maxilla. This case highlights successful treatment of maxillary Ewing's sarcoma using chemotherapy and radiation.
Area of Science:
- Oncology
- Pediatric Oncology
- Skeletal Tumors
Background:
- Ewing's sarcoma is a rare small round cell tumor, the second most common pediatric bone cancer.
- While typically affecting long bones, pelvis, and ribs, primary head and neck involvement, particularly the maxilla, is uncommon.
Observation:
- A rare case of primary non-metastatic Ewing's sarcoma of the left maxilla in an 11-year-old boy.
- Immunohistochemistry confirmed the diagnosis, showing positivity for CD 99 and FLI-1, and negativity for CD 45 and Tdt.
Findings:
- The patient received induction chemotherapy with alternating cycles of Vincristine, Adriamycin, Cyclophosphamide, Etoposide, and Ifosfamide.
- This was followed by radical conformal radiation therapy (55.8Gy in 31 fractions), resulting in a good response.
Implications:
- This case underscores the importance of considering Ewing's sarcoma in pediatric head and neck masses.
- Multimodal treatment involving chemotherapy and radiation can be effective for maxillary Ewing's sarcoma.

