Not just to survive but to thrive: delirium in the pediatric cardiac ICU

Saad Feroz1, Kathleen M Donnelly

  • 1Inova Children's Hospital, Falls Church, Virginia, USA.

Insights

Pediatric delirium is common in the pediatric cardiac intensive care unit (ICU), affecting up to 67% of patients. Strategies to normalize the ICU environment may reduce its incidence, but further research is needed on risk factors and long-term effects.

Area of Science:

  • Pediatric critical care medicine
  • Neuroscience
  • Pharmacology

Background:

  • Pediatric delirium is increasingly recognized in pediatric general and cardiac intensive care units (ICUs).
  • Validated screening tools are available for diagnosis.
  • Benzodiazepines are associated with increased delirium risk.

Purpose of the Study:

  • To review recent data on the prevalence, prevention, and management of pediatric delirium.
  • To highlight the relationship between sedation and delirium.
  • To identify areas for future research.

Main Methods:

  • Review of recent literature on pediatric delirium.
  • Analysis of prevalence data in pediatric cardiac ICU (PCICU) patients.
  • Discussion of risk factors, diagnostic tools, and treatment strategies.

Main Results:

  • Pediatric delirium affects up to 67% of patients in the PCICU.
  • Benzodiazepines are linked to delirium.
  • Normalization of the ICU environment may decrease incidence.
  • Antipsychotics are rarely needed after environmental normalization.

Conclusions:

  • Environmental normalization strategies, such as care bundles, may reduce pediatric delirium incidence.
  • Multi-institutional studies are needed to optimize prevention and treatment.
  • Long-term morbidities associated with pediatric delirium require further investigation.
Abstract

Related Concept Videos

Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
245
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
224
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
184
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
420
Cardiac Catheterization IV: Nursing Management01:26

Cardiac Catheterization IV: Nursing Management

Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
592
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
227