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Not just to survive but to thrive: delirium in the pediatric cardiac ICU
Saad Feroz1, Kathleen M Donnelly
1Inova Children's Hospital, Falls Church, Virginia, USA.
Insights
Pediatric delirium is common in the pediatric cardiac intensive care unit (ICU), affecting up to 67% of patients. Strategies to normalize the ICU environment may reduce its incidence, but further research is needed on risk factors and long-term effects.
Area of Science:
- Pediatric critical care medicine
- Neuroscience
- Pharmacology
Background:
- Pediatric delirium is increasingly recognized in pediatric general and cardiac intensive care units (ICUs).
- Validated screening tools are available for diagnosis.
- Benzodiazepines are associated with increased delirium risk.
Purpose of the Study:
- To review recent data on the prevalence, prevention, and management of pediatric delirium.
- To highlight the relationship between sedation and delirium.
- To identify areas for future research.
Main Methods:
- Review of recent literature on pediatric delirium.
- Analysis of prevalence data in pediatric cardiac ICU (PCICU) patients.
- Discussion of risk factors, diagnostic tools, and treatment strategies.
Main Results:
- Pediatric delirium affects up to 67% of patients in the PCICU.
- Benzodiazepines are linked to delirium.
- Normalization of the ICU environment may decrease incidence.
- Antipsychotics are rarely needed after environmental normalization.
Conclusions:
- Environmental normalization strategies, such as care bundles, may reduce pediatric delirium incidence.
- Multi-institutional studies are needed to optimize prevention and treatment.
- Long-term morbidities associated with pediatric delirium require further investigation.
Purpose Of Review:
Pediatric delirium has recently been recognized to occur frequently in the pediatric general and cardiac ICU. The purpose of this review is to highlight recent data on the prevalence, prevention, and management of this condition.
Recent Findings:
Pediatric delirium occurs in the pediatric cardiac ICU (PCICU) in as many as 67% of patients. Validated screening tools are now available to assist clinicians in the diagnosis of this condition. Research has shown a growing relationship between benzodiazepines, mainstays in the realm of sedation, and delirium. The full spectrum of risk factors has yet to be clearly elucidated. After normalization of the ICU environment, antipsychotics are infrequently required for treatment. While pediatric delirium has been associated with increased length of stay and cost, long-term morbidities are unknown at this time.
Summary:
Application of bundles to normalize the PCICU environment may lead to decreased incidence of pediatric delirium. Multiinstitutional studies are indicated to further delineate optimal bundles, stratify treatment strategies, and investigate long-term morbidity in pediatric delirium.
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