Related Experiment Video
Updated: Jan 6, 2026

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
Published on: May 16, 2025
Successful treatment of refractory edema with traditional herbal medicine: A case report
Gayoung Lee1,2,3, Jung-Hyo Cho2,3, Chang-Gue Son2,3
1Department of Internal Medicine, Cheonan Korean Medicine Hospital of Daejeon University.
Rationale:
Refractory edema is characterized by persistent swelling which does not react to diuretic use and sodium restriction. Traditional herbal medicine, Gwack Rhyung Tang and Chunggan extract effectively treated refractory lower limb edema caused by cirrhosis and improved liver function.
Patient Concerns:
A 64-year-old male patient with a history of hypertension, diabetes mellitus, hepatic encephalopathy, and cellulitis presented lower limb edema which did not react to diuretics for more than 7 months.
Diagnoses:
Refractory edema caused by cirrhosis.
Interventions:
The patient was treated for 25 days using Gwack Rhyung Tang and Chunggan extract.
Outcomes:
Loss of body weight, decrease in circumferences of both lower limb and improvement of liver function biochemistry results are checked. There was no recurrence or aggravation of the condition up to 3 weeks of follow-up periods.
Lessons:
Traditional herbal medicine can be an effective alternative for refractory edema due to cirrhosis with improving liver function.

