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Updated: Jan 6, 2026

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
Published on: November 3, 2023
[SICI-GISE/SIN Consensus document: Contrast-induced acute kidney injury in interventional cardiology]
Federico Ronco1, Lorenzo Azzalini2, Carlo Briguori3
1U.O.S.D. Emodinamica, Dipartimento Cardio-Toraco-Vascolare, Ospedale dell'Angelo, AULSS3 Serenissima, Mestre (VE).
Insights
Contrast-induced acute kidney injury (CI-AKI) is a significant risk for patients undergoing cardiac procedures. This consensus project disseminates strategies to prevent CI-AKI in interventional cardiology.
Area of Science:
- Nephrology and Cardiology
- Clinical Research
Background:
- Contrast-induced acute kidney injury (CI-AKI) poses a serious threat to patient outcomes after percutaneous procedures.
- Effective nephroprotection strategies are crucial in interventional cardiology.
Framework:
- A consensus project was initiated by the Italian Society of Interventional Cardiology (SICI-GISE).
- Collaboration with the Italian Society of Nephrology (SIN) ensured comprehensive expertise.
Implementation:
- The project focuses on disseminating evidence-based nephroprotection protocols.
- Implementation aims to standardize CI-AKI prevention in clinical practice.
Implications:
- Improved patient prognosis and reduced healthcare burden associated with CI-AKI.
- Enhanced integration of nephrology and cardiology practices for patient safety.
Abstract:
Contrast-induced acute kidney injury (CI-AKI) is a serious complication that can affect outcome and prognosis of patients undergoing percutaneous diagnostic and interventional procedures. The Italian Society of Interventional Cardiology (SICI-GISE) has promoted a consensus project on the subject of CI-AKI in order to disseminate and implement nephroprotection strategies in interventional cardiology. The initiative was conducted in partnership with the Italian Society of Nephrology (SIN).
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Acute Kidney Injury I: Introduction
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Acute Kidney Injury II: Pathophysiology
Acute Kidney Injury III: Clinical Manifestations

