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Structural Isomerism

Structural Isomerism

Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
Linkage isomers occur when the coordination compound contains a ligand that can bind to the transition metal center through two different atoms. For example, the CN− ligand can bind through the carbon atom or through the nitrogen atom. Similarly, SCN− can...

Coordination Number and Geometry

Coordination Number and Geometry

For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar.

Metal-Ligand Bonds

Metal-Ligand Bonds

The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...

Coordination Compounds and Nomenclature

Coordination Compounds and Nomenclature

In most main group element compounds, the valence electrons of the isolated atoms combine to form chemical bonds that satisfy the octet rule. For instance, the four valence electrons of carbon overlap with electrons from four hydrogen atoms to form CH4. The one valence electron leaves sodium and adds to the seven valence electrons of chlorine to form the ionic formula unit NaCl (Figure 1a). Transition metals do not normally bond in this fashion. They primarily form coordinate covalent bonds, a...

Stereoisomerism

Stereoisomerism

Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...

Valence Bond Theory

Valence Bond Theory

Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...

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Updated: Jan 6, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Published on: May 28, 2014

Coordination complexes involving sydnones as ligands.

Xavier Bantreil¹, Nicolas Pétry¹, Frédéric Lamaty¹

¹Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, CNRS, Université de Montpellier, ENSCM, Campus Triolet, Place Eugène Bataillon, 34095 Montpellier Cedex 5, France. frederic.lamaty@umontpellier.fr xavier.bantreil@umontpellier.fr.

Dalton Transactions (Cambridge, England : 2003)

|October 9, 2019

Summary

Sydnones, versatile mesioionic compounds, are explored for creating novel coordination complexes. Their unique structure allows for metalation, ligand modification, and property tuning, offering synthetic and biological advantages.

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Last Updated: Jan 6, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

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Line Shape Analysis of Dynamic NMR Spectra for Characterizing Coordination Sphere Rearrangements at a Chiral Rhenium Polyhydride Complex

Line Shape Analysis of Dynamic NMR Spectra for Characterizing Coordination Sphere Rearrangements at a Chiral Rhenium Polyhydride Complex

Published on: July 27, 2022

Area of Science:

* Coordination Chemistry
* Organic Synthesis
* Medicinal Chemistry

Background:

* Sydnones are mesioionic compounds known for diverse reactivity.
* Previous research focused on substitution and cycloaddition reactions.
* Limited exploration of sydnones in coordination chemistry.

Purpose of the Study:

* To provide a perspective on the application of sydnones in coordination complexes.
* To highlight synthetic strategies for incorporating sydnones into ligands.
* To discuss the influence of sydnone moieties on complex properties.

Main Methods:

* Review of literature on sydnone chemistry and coordination complexes.
* Analysis of metalation strategies on the sydnone ring.
* Examination of sydnone modification for polydentate ligand design.

Main Results:

* Sydnones can be incorporated into coordination complexes via direct metalation.
* Modification of sydnones yields versatile polydentate ligands.
* The polar nature of sydnones influences the electronic and steric properties of complexes.

Conclusions:

* Sydnones offer a unique platform for designing novel coordination complexes.
* These complexes possess potential in both synthetic methodologies and biological applications.
* Further research into sydnone-based coordination chemistry is warranted.