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Floppy eyelid syndrome: A comprehensive review
Ricardo Salinas1, Madeleine Puig1, Constance L Fry1
1Department of Ophthalmology, Long School of Medicine, University of Texas Health at San Antonio, San Antonio, TX, USA.
The Ocular Surface
|October 9, 2019
Summary
Floppy eyelid syndrome (FES) involves eyelid laxity and conjunctivitis, often linked to keratoconus or sleep apnea. Treatment ranges from conservative measures to surgery, with continuous positive airway pressure aiding those with sleep apnea.
Area of Science:
- Ophthalmology
- Sleep Medicine
Background:
- Floppy eyelid syndrome (FES) is characterized by eyelid hyperlaxity and reactive palpebral conjunctivitis.
- It frequently co-occurs with ocular conditions like keratoconus and systemic diseases such as obstructive sleep apnea (OSA).
Purpose of the Study:
- To provide a comprehensive review of Floppy Eyelid Syndrome.
- To cover its epidemiology, pathology, pathogenesis, clinical features, and treatment options.
Main Methods:
- Literature review of existing studies on Floppy Eyelid Syndrome.
- Synthesis of information regarding diagnosis, associated conditions, and therapeutic interventions.
Main Results:
- FES presents with easily everted eyelids and chronic upper eyelid papillary conjunctivitis.
- Conservative management includes lubrication and eye shields; continuous positive airway pressure (CPAP) can improve symptoms in OSA patients.
- Surgical correction is effective for refractory cases.
Conclusions:
- FES is a common cause of ocular irritation that requires evaluation.
- Management strategies should be tailored to individual patient needs, considering associated conditions.
- Early diagnosis and appropriate treatment can significantly improve patient outcomes.

