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The Rome IV: Irritable bowel syndrome - A functional disorder
Per M Hellström1, Peter Benno1
1Department of Medical Sciences, Gastroenterology and Hepatology, Uppsala University, Uppsala, Sweden.
The Rome IV consensus provides updated criteria for functional gastrointestinal disorders, emphasizing gut-brain interaction and microflora. While robust, it may require further refinement with biomarkers for comprehensive patient diagnosis and treatment.
Area of Science:
- Gastroenterology
- Clinical Medicine
Background:
- Functional gastrointestinal disorders (FGIDs) are highly prevalent in gastroenterology.
- The Rome process has established evolving consensus definitions and diagnostic criteria for FGIDs.
Purpose of the Study:
- To summarize key changes in the Rome IV consensus compared to Rome III.
- To highlight advancements in understanding FGIDs, including gut-brain interaction and microflora.
Main Methods:
- Review of the Rome IV consensus criteria.
- Comparison of Rome IV with the previous Rome III (2006) guidelines.
- Discussion of limitations and potential improvements for FGID diagnosis.
Main Results:
- Rome IV introduces updated diagnostic criteria for FGIDs.
- Key changes include focus on basal normative values, gut-brain interaction, and microflora.
- Limitations persist, indicating potential for improved diagnostic accuracy.
Conclusions:
- The Rome IV consensus offers a strong framework for FGID research and clinical practice.
- Integration of exclusion criteria and biomarkers could enhance diagnostic precision.
- A biopsychosocial approach is recommended for optimizing patient compliance and outcomes in gastroenterology.
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