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Updated: Jan 6, 2026

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
Published on: July 11, 2025
Development of a real-time endoscopic image diagnosis support system using deep learning technology in colonoscopy
Masayoshi Yamada1,2, Yutaka Saito3, Hitoshi Imaoka4
1Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan. masyamad@ncc.go.jp.
An artificial intelligence (AI) system was developed to detect early colorectal cancer signs during colonoscopy, significantly improving detection rates for challenging non-polypoid lesions. This AI tool aids endoscopists by providing real-time alerts, reducing missed abnormalities and enhancing early disease detection.
Area of Science:
- Medical technology
- Artificial intelligence in healthcare
- Gastroenterology
Background:
- Colonoscopy skills vary among endoscopists, leading to missed colorectal neoplasms.
- Early detection of colorectal cancer is crucial for improving patient outcomes.
- A need exists for advanced tools to assist in identifying subtle lesions.
Purpose of the Study:
- To develop a real-time artificial intelligence (AI) system for automatic detection of early colorectal cancer signs during colonoscopy.
- To enhance the detection of difficult-to-identify non-polypoid lesions.
- To reduce the rate of missed abnormalities during colonoscopy procedures.
Main Methods:
- Development of an AI system trained to automatically detect early colorectal cancer indicators.
- Evaluation of the AI system's performance using sensitivity, specificity, and area under the curve (AUC) metrics.
- Optimization of the AI model through tensor metric decomposition for accelerated image processing (21.9 ms/image).
Main Results:
- The AI system demonstrated high performance in the validation set: 97.3% sensitivity and 99.0% specificity (AUC 0.975).
- Sensitivity was particularly high for polypoid (98.0%) and non-polypoid (93.7%) subgroups.
- The system provides real-time predictions, aiding endoscopists in identifying lesions quickly.
Conclusions:
- The developed AI system is effective in supporting endoscopists for high detection rates, especially for non-polypoid lesions often missed.
- Real-time alerts from the AI system can prevent the omission of abnormalities during colonoscopy.
- This technology holds significant potential for improving the early detection of colorectal cancer.
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