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Neurology-Psychiatry Interface: Uncommon Presentation of Moyamoya Disease

Shipra Singh1, Priyanka Hooda1, Nishtha Singh1

  • 1Department of Psychiatry, Post Graduate Institute of Medical Education and Research (PGIMER), Dr. Ram Manohar Lohia Hospital, Delhi, India.

Journal of Neurosciences in Rural Practice
|October 10, 2019
PubMed

Insights

Moyamoya disease (MMD) can cause neuropsychiatric symptoms, delaying diagnosis. Early recognition of these behavioral changes is crucial for timely MMD treatment and improved patient outcomes.

Area of Science:

  • Neurology
  • Neuropsychiatry

Background:

  • Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by progressive stenosis of the internal carotid arteries and their branches.
  • MMD typically presents with ischemic stroke, but neuropsychiatric manifestations are increasingly recognized.

Observation:

  • A case study of an adult female with MMD presenting with prominent behavioral symptoms including irritability, suspiciousness, and cognitive deficits.
  • The patient experienced headache and difficulties with object and facial recognition, impacting daily activities.

Findings:

  • The patient's neuropsychiatric symptoms were the primary presenting complaints, leading to a significant delay in diagnosing Moyamoya disease.
  • This case highlights the potential for MMD to manifest with severe behavioral disturbances mimicking primary psychiatric disorders.

Implications:

  • Increased awareness of neuropsychiatric symptoms in MMD is essential for early diagnosis and intervention.
  • Prompt evaluation of behavioral changes in patients with suspected MMD can prevent diagnostic delays and improve neurological outcomes.
Keywords:
moyamoya diseasepsychosisvascular headache

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