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Updated: Jan 6, 2026

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Salen/salan metallic complexes as redox labels for electrochemical aptasensors
Amani Ben Jrad1, Hussein Kanso2, Delphine Raviglione3
1Université Perpignan Via Domitia, Biocapteurs-Analyses-Environnement, F-66860, Perpignan, France. carole.blanchard@univ-perp.fr and Laboratoire de Biodiversité et Biotechnologies Microbiennes, USR 3579 Sorbonne Universités (UPMC) Paris 6 et CNRS Observatoire Océanologique, F-66650, Banyuls-sur-Mer, France and USR 3278 CRIOBE, PSL Research University, EPHE-UPVD-CNRS, Université de Perpignan Via Domitia, Laboratoire d'Excellence "CORAIL", Bâtiment T, 58 avenue P. Alduy, 66860 Perpignan, France. nicolas.inguimbert@univ-perp.fr.
Abstract:
This work presents the synthesis and characterization of salen/salan metal complexes for their future application as electrochemical labels in affinity sensors. Due to its stability and electrochemical properties, an oxovanadium salan complex was selected and coupled to an estradiol-specific aptamer. The response of the resulting aptasensor was shown to decrease with increasing estradiol concentration.
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