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Clinical Experience of Aortic Valve Surgery in Patients With Aortitis Disease

Yunxing Xue1, Jun Pan, Qing Zhou

  • 1Department of Thoracic and Cardiovascular Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China. albert_xue@163.com.

The Heart Surgery Forum
|October 10, 2019
PubMed

Insights

Aortic valve surgery in aortitis patients shows similar outcomes between arteritis and Behcet's disease groups, though Behcet's disease patients had more redo operations due to valve issues.

Area of Science:

  • Cardiovascular Surgery
  • Rheumatology
  • Vascular Surgery

Background:

  • Aortitis, a group of inflammatory conditions affecting the aorta, can lead to significant aortic valve complications.
  • Management of aortic valve disease in patients with aortitis presents unique challenges.
  • Understanding surgical outcomes is crucial for optimizing patient care.

Purpose of the Study:

  • To evaluate the clinical experience and outcomes of aortic valve surgery in patients with aortitis.
  • To compare surgical results between patients with different types of aortitis, specifically arteritis and Behcet's disease.
  • To identify factors influencing surgical success and complications.

Main Methods:

  • Retrospective analysis of 15 patients with aortitis undergoing aortic valve surgery between 2010 and 2018.
  • Patients were categorized into an Arteritis Group (n=8) and a Behcet's Disease (BD) Group (n=7).
  • Surgical procedures included valvuloplasty, valve replacement, and root replacement (Bentall procedure).

Main Results:

  • While overall morbidity and mortality were similar, the BD Group experienced a significantly higher incidence of redo operations (57.1%) due to paravalvular leak or valve insufficiency compared to the Arteritis Group (0%, P=.026).
  • Mechanical ventilation time was longer in the BD Group.
  • Preoperative parameters and surgical approaches were comparable between the groups.

Conclusions:

  • Aortic valve surgery in aortitis patients requires careful consideration of the underlying inflammatory condition.
  • Specialized surgical techniques may be necessary to mitigate risks such as prosthetic valve detachment.
  • Behcet's disease patients may have a higher risk of reoperation after aortic valve surgery.
Abstract

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