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Computer modeling and in vitro experimental study of water-cooled microwave ablation array
Dui-Dui Chen1, Yu-Xin Du2, Zu-Bing Chen1
1Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan University, Wuhan, China.
Summary
A novel water-cooled double-needle microwave ablation (MW) array shows improved tumor ablation zones compared to single-needle devices. This technology offers potential advantages for effective tumor treatment.
Area of Science:
- Medical Engineering
- Biomedical Devices
- Thermal Ablation Technologies
Background:
- Microwave (MW) ablation offers rapid heating and large ablation zones for tumor treatment.
- Current single-needle MW devices are widely used in clinical practice.
- A new water-cooled double-needle MW ablation array has been developed.
Purpose of the Study:
- To present a research protocol for evaluating a novel water-cooled double-needle MW ablation array.
- To compare the performance of the new array against a standard single-needle MW device.
- To assess the potential advantages of the new array for tumor ablation.
Main Methods:
- Computer modeling using the finite element method (FEM) to predict temperature distributions.
- Tissue-mimicking phantom experiments to evaluate ablation dimensions.
- In vitro swine liver experiments to compare ablation efficacy of the new array and a single-needle device.
Main Results:
- FEM predicted a maximum transverse ablation diameter (MTAD) of 4.2 cm at 100 W for 300 s.
- Phantom experiments showed MTADs of 2.6 cm (single-needle) and 4 cm (double-needle array).
- In vitro swine liver experiments yielded MTADs of 2.82 cm (single-needle) and 3.85 cm (double-needle array) at 100 W for 300 s.
Conclusions:
- A new water-cooled double-needle MW ablation array has been designed and experimentally validated.
- The developed array demonstrated a larger ablation zone compared to the single-needle device.
- This novel array shows promise for enhanced tumor ablation efficacy.
