Response of abdominal muscle to graded mechanical loads

Abdominal muscle electromyograms were monitored in response to graded mechanical loads added to either inspiration or expiration in anesthetized cats. The surgical preparation, the apparatus, and the levels of loads applied (resistive, tracheal occlusion, and continuous positive pressure) were matched with those employed in our previous study on medullary expiratory neurons [Baker et al, 1979]. Although expiratory neuron firing was significantly increased by each of three graded levels of expiratory resistive loads, abdominal muscles were activated in only about 50% of the animals exposed to the highest-level resistive load. The smaller resistive loads failed to elicit any discernible abdominal muscle activity. These findings suggest that the lower motor neurons have a higher threshold for activation than the medullary neurons. Recruitment of medullary expiratory neurons and integration of synaptic input at the spinal level must play important roles in the response to expiratory loading. Abdominal muscles did not respond to mechanical loading during inspiration. Bilateral cervical vagotomy eliminated the abdominal muscle responses to expiratory loads.