Related Experiment Video
Updated: Jan 6, 2026

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug
Published on: May 17, 2024
Treating Uncontrolled Hypertension with Hibiscus sabdariffa When Standard Treatment Is Insufficient: Pilot
Marwah Al-Anbaki1, Renata Campos Nogueira1, Anne-Laure Cavin1
1Antenna Foundation, Geneva, Switzerland.
Abstract:
To assess the use of Hibiscus sabdariffa (HS), known as karkade in Jordan, in cases of uncontrolled hypertension, either with or without medication, as validated by several clinical trials. A multicentric pilot clinical study. Outside a refugee camp in Jordan. Thirty-eight participants with blood pressure (BP) above 140/90 mmHg consumed H. sabdariffa tea. Consumption of karkade tea containing 10 g of HS/0.5 L daily. This dosage was increased to 15 g of HS/1 L and to 20 g of HS/1 L during the second and third weeks, respectively, if their BP was still high. The primary outcome measurement was blood measurement taken once a week. Secondary outcome measurements were satisfaction, possible side effects, and interactions with other medications. Of the 38 participants, 29 finished the program, 72% of whom were taking antihypertensive medication due to uncontrolled hypertension and 28% of whom were not. H. sabdariffa was generally well tolerated: 38% of participants reached the target BP at the end of the study and 65% saw their systolic BP decrease by at least 10 mmHg. H. sabdariffa (karkade) is generally well tolerated and seems to be helpful in treating uncontrolled hypertension, with or without medication.
Related Concept Videos
Hypertension IV: Drug Therapy and Lifestyle Modifications
Heart Failure V: Medical Management
Hypertension V: Nursing Management
Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...
Hypertension III: Clinical Manifestations and Diagnostic Studies
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

