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Vascular endothelial function is improved after active mattress use.

Gary Baker1, Saul Bloxham2, Joe Laden2

  • 1Dreemflow Limited, Plymouth, Devon.

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|October 11, 2019
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Summary
This summary is machine-generated.

Eight weeks of active mattress use significantly improved vascular endothelial function, including resting blood flow and skin temperature, in healthy individuals. This suggests active mattresses may enhance endothelial health.

Keywords:
active mattressendothelial functionhypertensionpost occlusive reactive hypemiapressure ulcerssupport surface

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Area of Science:

  • Physiology
  • Vascular Biology
  • Biomedical Engineering

Background:

  • Active mattresses provide pressure relief to prevent pressure ulcers.
  • No studies have directly assessed the vascular endothelial response to long-term active mattress use.
  • Understanding endothelial function is crucial for cardiovascular health.

Purpose of the Study:

  • To investigate the hypothesis that eight weeks of active mattress use improves vascular endothelial function in healthy participants.
  • To assess changes in physiological parameters related to endothelial function.
  • To evaluate the long-term effects of active mattress use.

Main Methods:

  • Recruited 10 healthy participants (4 male, 6 female).
  • Assessed baseline skin temperature (BskT), resting blood flow (RBF), and endothelial function (post-occlusive reactive hyperaemia - PORH) at baseline, 8 weeks, and 16 weeks.
  • Participants slept on an active mattress for 8 weeks.

Main Results:

  • Significant increases in RBF (336%), PORH (197%), and BskT (3.5°C) were observed after 8 weeks of active mattress use.
  • RBF increased from 24.3±38.3 to 106.0±100.3 perfusion units (p=0.021).
  • PORH increased from 13,456±10,225 to 40,252±23,995 perfusion units x seconds (p=0.003), and BskT increased from 22.9±2.5°C to 26.4±1.9°C (p<0.001).

Conclusions:

  • Eight weeks of active mattress use significantly improves RBF, PORH, and BskT.
  • These findings suggest that active mattress use can enhance endothelial function.
  • Further research is warranted to explore the potential of active mattresses in managing conditions benefiting from improved endothelial function.