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Lymphocyte reference intervals in the era of newborn screening

Thomas A Fleisher1, Sergio D Rosenzweig1

  • 1Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Md.

The Journal of Allergy and Clinical Immunology
|October 11, 2019
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Flow cytometryestimated gestational agelymphocytenewborn screeningnormal rangeprematuritysevere combined immunodeficiency

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Development of Immunocompetence01:22

Development of Immunocompetence

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
745

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