Cross-cultural adaptation and validation of the RhinAsthma Patient Perspective (RAPP) in Spanish

Area of Science:

• Respiratory Medicine
• Quality of Life Research
• Psychometrics

Background:

• The RhinAsthma Patient Perspective (RAPP) is the sole instrument for evaluating health-related quality of life (HRQoL) in daily clinical practice for patients with asthma and allergic rhinitis (AR).
• Cross-cultural adaptation and validation are essential for the accurate assessment of HRQoL in diverse linguistic populations.

Purpose of the Study:

• To perform a cross-cultural validation of the RAPP questionnaire in Spanish.
• To establish the psychometric properties of the Spanish version of the RAPP for use in clinical settings.

Main Methods:

• The RAPP questionnaire was translated into Spanish.
• 149 adult patients with asthma and AR were recruited and assessed twice over a four-week interval.
• Psychometric properties including factor structure, internal consistency, reliability, validity, and responsiveness were evaluated.

Main Results:

• Exploratory and confirmatory factor analyses confirmed a uni-dimensional structure.
• Satisfactory internal consistency (0.73-0.87), reliability (ICC=0.69, CCC=0.74), and validity (p<.05) were observed.
• The questionnaire demonstrated responsiveness, with significant associations with VAS (r=0.28) and ACT (r=-0.35), and a minimal clinically important difference (MCID) of 2.

Conclusions:

• The Spanish version of the RAPP exhibits robust psychometric properties.
• It is a valid, reliable, and responsive instrument for assessing HRQoL in patients with asthma and AR in Spanish-speaking clinical practice.