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Optimizing neoadjuvant radiotherapy for resectable and borderline resectable pancreatic cancer using protons
Romaine Charles Nichols1, Michael Rutenberg2
1Department of Radiation Oncology, University of Florida College of Medicine, Jacksonville, FL 32206, United States. rnichols@floridaproton.org.
Proton therapy for pancreatic cancer shows promise in improving local-regional control without increasing surgical complications. This approach offers a potential solution for enhancing treatment outcomes in resectable pancreatic cancer patients.
Area of Science:
- Oncology
- Radiation Oncology
- Surgical Oncology
Background:
- Pancreatic cancer has a low cure rate (20%) even in resectable cases.
- High local-regional failure rates (over 50%) occur post-pancreatectomy.
- Systemic therapies have limited impact on local-regional disease control.
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