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Updates in imaging in ocular oncology.

Jose R Davila1, Prithvi Mruthyunjaya1

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Summary

Advanced ophthalmic imaging, including optical coherence tomography (OCT) and OCT angiography, enhances the diagnosis and understanding of ocular tumors like retinoblastoma and uveal melanoma. These technologies aid in early detection and risk stratification of eye cancers.

Keywords:
Ocular oncologyangiographymelanomaocular surface squamous neoplasiaoptical coherence tomographyradiation retinopathyretinoblastoma

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Area of Science:

  • Ophthalmology
  • Oncology
  • Medical Imaging

Background:

  • Ophthalmic imaging innovations significantly impact ophthalmic disease diagnosis and treatment.
  • Ocular oncology benefits from advanced imaging for detailed visualization of tumors.

Purpose of the Study:

  • To review the impact of new ophthalmic imaging technologies on ocular oncology.
  • To highlight the role of optical coherence tomography (OCT) and OCT angiography in diagnosing and understanding eye cancers.

Main Methods:

  • Utilized enhanced depth imaging and swept source OCT for detailed visualization of retinoblastoma and uveal melanoma.
  • Employed OCT angiography for non-invasive imaging of retinal and uveal vasculatures.

Main Results:

  • OCT provides unprecedented anatomical detail of ocular tumors, improving understanding of vision loss pathophysiology.
  • New imaging modalities detect "invisible" tumors and risk-stratify pre-malignant lesions, supporting their use in screenings.
  • OCT angiography reveals vascular changes linked to malignant transformation and radiation-induced vision loss.

Conclusions:

  • Advanced OCT technologies offer superior visualization for diagnosing and managing ocular tumors.
  • OCT angiography provides crucial insights into vascular dynamics in ocular oncology.
  • While long-term clinical impact is pending, emerging data suggests promising outcomes for new imaging in eye cancer care.