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One-Month Follow-Up of Patients with Unspecified Abdominal Pain Referring to the Emergency Department; a Cohort Study
Seyed Mohammad Hoseininejad, Reza Jahed, Mohammad Sazgar1
1Emergency Department, Mazandaran University of Medical Sciences, Sari, Iran.
Insights
Many patients with abdominal pain leave the emergency department (ED) without a diagnosis. A one-month follow-up revealed that older age, leukocytosis, and outpatient visits improve diagnostic outcomes for unspecified abdominal pain.
Area of Science:
- Gastroenterology
- Emergency Medicine
- Internal Medicine
Background:
- A significant proportion of emergency department (ED) visits for abdominal pain result in discharge without a definitive diagnosis.
- Unspecified abdominal pain presents a diagnostic challenge, impacting patient outcomes and healthcare resource utilization.
Purpose of the Study:
- To investigate the one-month clinical outcomes of patients presenting to the ED with unspecified abdominal pain.
- To identify factors associated with establishing a clear diagnosis in patients initially discharged with undiagnosed abdominal pain.
Main Methods:
- A prospective cohort study involving patients evaluated for unspecified abdominal pain in the ED and followed for one month.
- Patients were categorized into groups with a clear or unclear cause of abdominal pain at follow-up, and their characteristics were compared.
Main Results:
- After one month, 44.7% of patients still experienced abdominal pain, and a definitive diagnosis was established in 58.7% of cases.
- Significant differences between groups were observed in pain location, age, and history of comorbid diseases.
- Leukocytosis (OR: 5.92), older age (OR: 2.78), and outpatient follow-up (OR: 1.04) were predictive factors for establishing a clear diagnosis.
Conclusions:
- Nearly 40% of patients discharged with unspecified abdominal pain remain undiagnosed after one month.
- Initial leukocytosis, older age, and consistent outpatient follow-up are key indicators for achieving a diagnosis in these patients.
Introduction:
About one third of patients referring to emergency department (ED) with abdominal pain, are discharged without a definite diagnosis. This study aimed to investigate the one-month outcome of patients with unspecified abdominal pain.
Methods:
This cohort study was conducted on subjects who were evaluated in ED with unspecified abdominal pain and were referred to the gastroenterology clinic and followed for one month. Finally, they were divided into two groups of cases with clear cause of abdominal pain and unclear cause of abdominal pain and patients' characteristics were compared between the groups.
Results:
150 cases with the mean age of 40.68 ± 18.34 years were studied (53.3% female). After one month, 67 (44.7%) patients still complained of abdominal pain. A definitive cause of abdominal pain was established in 88 (58.7%) cases. There was not any significant difference between groups regarding, sex distribution (p = 012), duration of pain (p = 0.11), history of previous similar pain (p = 0.136), pain radiation (p = 0.737), length of hospital stay (p = 0.51), and presence of anorexia (p = 0.09), nausea and vomiting (p= 0.50), fever (p = 1.0), diarrhea (p = 0.23), and constipation (p = 0.07). There was a significant difference between the groups regarding location of pain (p = 0.017), age (p = 0.001) and history of comorbid diseases (p = 0.046). The predictive factors of finding a clear cause for abdominal pain in one-month follow-up, were leukocytosis (OR: 5.92 (95% CI: 2.62 - 13.39); p < 0.001), age (OR: 2.78 (95% CI: 1.15 - 6.71); p = 0.023), and outpatient follow-up (OR: 1.04 (95% CI: 1.02 - 1.07); p < 0.001).
Conclusion:
Approximately, 40% of patients who were discharged with unspecified abdominal pain did not receive a clear diagnosis after one month of follow-up. Older age, leucocytosis in initial evaluations, and outpatient follow-up increased the probability of finding a clear cause for abdominal pain in the mentioned cases.
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